The first step is to define your research question. A concise research question is the back-bone for a good search strategy, as it determines the structure and sequence for your literature searches.
For preclinical reviews, a research question typically contains the following components:
(b) disease or condition of interest
(c) animal species/cell population studied
(d) outcome measures
An ideal format for a preclinical research question could then be:
‘What is the effect of [treatment/intervention] on [outcome measures] in [animal species/cell population studied] for [disease or condition of interest]?'
Before you start on your systematic review make sure the your systematic review question has not been investigated before, check the Systematic Review Library.
References & Resources:
Leenaars et al (2012) A step-by-step guide to systematically identify all relevant animal studies
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